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Palmitoylethanolamide (PEA) is a body-produced fatty acid that can be your secret weapon against inflammation and pain. This natural peripheral pain reliever is made on-demand to target soreness and lower irritation at the site of injury. Even though your body manufactures PEA, reinforcing it with a supplement may help tackle the root of your pang. Acetaminophen and NSAIDs are often used to treat pain, but their side effects make them a risk. PEA doesn't have any documented side effects and won't harm your cardiovascular or organ health, making it a safer, long-term option.